Nelune Comprehensive Cancer Centre
Three-dimensional brachytherapy planning has lead to more accurate assessment of doses received by OAR during high dose rate (HDR) cervix brachytherapy. However, the debate continues regarding optimal bladder volume and the dosimetric effect on the surrounding OAR. The purpose of this single institutional retrospective review was to investigate inter-fraction bladder volume and establish a correlation between bladder volume and its effects on doses received by OAR (urinary bladder, rectum, sigmoid colon). This dosimetric analysis was conducted retrospectively on patients who underwent more than one fraction of HDR cervix brachytherapy during 2016 to 2018 at the Nelune Comprehensive Cancer Centre (NCCC). Each patient’s computed tomography plan, structure volumes (contoured in Oncentra), and three-dimensional dose volume histogram (DVH) parameters for bladder and other OAR, were compared for each fraction to identify if the bladder volume impacted the doses received by OAR. Early data analysis indicated that there was inter-fraction bladder volume variation, however further analysis is required to determine the effect on OAR. Other studies have suggested that there is a relationship between the volumes of OAR and their received doses. It is therefore hypothesized that further analysis will prove that bladder volume variation does impact the OAR doses.
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